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Major PK Uncertainties: Translational Scaling : The PK parameters (especially clearance rates and effective doses) observed in small animals do not reliably scale up to humans

Key areas of investigation include modulation of the nitric oxide (NO) system through interaction with NOS isoforms, upregulation of growth factor receptors (including VEGFR2 and EGF receptor systems), and engagement of the FAK-paxillin signaling cascade associated with cell migration and adhesion

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I have also noticed a smoother texture and a reduction in blemishes